Inducible HIV-1 Reservoir Quantification: Clinical Relevance, Applications and Advancements of TILDA.. Lungu, C., Banga, R., Gruters, R., & Procopio, A. F. (2021). Front. Microbiol. 2021 Jun 15. doi.org/10.3389/fmicb.2021.686690.

Augmenting the Immune Response against a Stabilized HIV-1 Clade C Envelope Trimer by Silica Nanoparticle Delivery. Peterhoff, D., Thalhauser, S., Sobczak, J. M., Mohsen, M. O., Voigt, C., Seifert, N., Neckermann, P., Hauser, A., Ding, S., Sattentau, Q., Bachmann, M. F., Breunig, M., & Wagner, R. (2021). Vaccines, 9(6):642. 2021 Jun 11. doi.org/10.3390/vaccines9060642.

Selective cell death in HIV-1-infected cells by DDX3 inhibitors leads to depletion of the inducible reservoir. Rao, S., Lungu, C., Crespo, R., Steijaert, T. H., Gorska, A., Palstra, R. J., Prins, H., van Ijcken, W., Mueller, Y. M., van Kampen, J., Verbon, A., Katsikis, P. D., Boucher, C., Rokx, C., Gruters, R. A., & Mahmoudi, T.  (2021). Nature communications12(1), 2475. 2021 Apr 30. doi.org/10.1038/s41467-021-22608-z.

Inter-Laboratory Reproducibility of Inducible HIV-1 Reservoir Quantification by TILDA. Lungu, C., Procopio, F. A., Overmars, R. J., Beerkens, R., Voermans, J., Rao, S., Prins, H., Rokx, C., Pantaleo, G., Vijver, D., Mahmoudi, T., Boucher, C., Gruters, R. A., & Kampen, J. (2020). Viruses, 12(9), 973. 2020 Sep 02. doi.org/10.3390/v12090973.

Induction of Identical IgG HIV-1 Envelope Epitope Recognition Patterns After Initial HIVIS-DNA/MVA-CMDR Immunization and a Late MVA-CMDR Boost. Joachim, A., Ahmed, M., Pollakis, G., Rogers, L., Hoffmann, V. S., Munseri, P., Aboud, S., Lyamuya, E. F., Bakari, M., Robb, M. L., Wahren, B., Sandstrom, E., Nilsson, C., Biberfeld, G., Geldmacher, C., & Held, K. (2020). Frontiers in immunology11, 719. 2020 Apr 28. doi.org/10.3389/fimmu.2020.00719.

Multi-arm multi-stage randomised controlled trials for evaluating therapeutic HIV cure interventions. Moore, C., Stöhr, W., Crook, A. M., Richert, L., Leliévre, J-D.,  Pantaleo, G., García, F., Vella, S., Lévy, Y., Thiébaut, R.,  McCormack, S. (2019). Lancet HIV, 6(5):e334-e340. 2019 May 01. doi: 10.1016/S2352-3018(19)30082-7.

Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence. Nadai, Y., Held, K., Joseph, S., Ahmed, M., Hoffmann, V. S., Peterhoff, D., Missanga, M., Bauer, A., Joachim, A., Reimer, U., Zerweck, J., McCormack, S., Cope, A. V., Tatoud, R., Shattock, R. J., Robb, M. L., Sandstroem, E. G., Hoelscher, M., Maboko, L., Bakari, M., Kroidl, A., Wagner, R., Weber, J., Pollakis, G., & Geldmacher, C. (2019). Frontiers in immunology10, 717. 2019 Apr 24. doi.org/10.3389/fimmu.2019.00717.

A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost Vaccine Regimens. Kratochvil, S., McKay, P. F., Kopycinski, J. T., Bishop, C., Hayes, P. J., Muir, L., Pinder, C. L., Cizmeci, D., King, D., Aldon, Y., Wines, B. D., Hogarth, P. M., Chung, A. W., Kent, S. J., Held, K., Geldmacher, C., Dally, L., Santos, N. S., Cole, T., Gilmour, J., Fidler, S., & Shattock, R. J. (2017). Frontiers in immunology8, 595. 2017 May 24. doi.org/10.3389/fimmu.2017.00595. 

A Comparative Phase I Study of Combination, Homologous Subtype-C DNA, MVA, and Env gp140 Protein/Adjuvant HIV Vaccines in Two Immunization Regimes. Joseph, S., Quinn, K., Greenwood, A., Cope, A. V., McKay, P. F., Hayes, P. J., Kopycinski, J. T., Gilmour, J., Miller, A. N., Geldmacher, C., Nadai, Y., Ahmed, M. I., Montefiori, D. C., Dally, L., Bouliotis, G., Lewis, D. J., Tatoud, R., Wagner, R., Esteban, M., Shattock, R. J., … Weber, J. (2017). Frontiers in immunology8, 149. 2017 Feb 22. doi.org/10.3389/fimmu.2017.00149.

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This project has received funding from the European Union's Horizon 2020 research
and innovation programme under grant agreement N° 681032